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Article

<scp>L</scp>‐type amino acid transporter 1 as a potential molecular target in human astrocytic tumors

22 Feb 2006

Abstract excerpt

L-type amino acid transporter 1 (LAT1) is a Na+-independent neutral amino acid transport agency and essential for the transport of large neutral amino acids. LAT1 has been identified as a light chain of the CD98 heterodimer from C6 glioma cells. LAT1 also corresponds to TA1, an oncofetal antigen that is expressed primarily in fetal tissues and cancer cells. We have investigated for the first time, the expression...

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PMID: 16496379
DOI: 10.1002/ijc.21866

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