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Article

LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells

28 Jul 2016

Abstract excerpt

L-type amino acid transporter 1 (LAT1, SLC7A5) incorporates essential amino acids into cells. Recent studies have shown that LAT1 is a predominant transporter in various human cancers. However, the function of LAT1 in thymic carcinoma remains unknown. Here we demonstrate that LAT1 is a critical transporter for human thymic carcinoma cells. LAT1 was strongly expressed in human thymic carcinoma tissues....

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PMID: 27567475
DOI: 10.1016/j.jphs.2016.07.006

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