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Article

Risk of colorectal cancer in monoallelic and biallelic carriers of MYH mutations: a population-based case-family study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2006

Jenkins Mark A, Croitoru Marina E, Monga Neerav, Cleary Sean P, Cotterchio Michelle, Hopper John L, Gallinger Steven

Abstract excerpt

Previous case-control studies have suggested that carriers of monoallelic germline mutations in the MYH gene may be at increased risk of colorectal cancer. We applied a kin-cohort design, using a modified segregation analysis, to estimate the colorectal cancer risk using 300 first-degree relatives of 39 colorectal cancer cases who were monoallelic or biallelic carriers of MYH mutations. We found that monoallelic...

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PMID: 16492921
DOI: 10.1158/1055-9965.EPI-05-0793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Risk of colorectal cancer in monoallelic and biallelic carriers of MYH mutations: a population-based case-family study.PMID 16492921Read ↗

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