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The role of MYH gene in genetic predisposition to colorectal cancer: another piece of the puzzle.

Cancer letters - 18 Sept 2008

Avezzù Alessandra, Agostini Marco, Pucciarelli Salvatore, Lise Mauro, Urso Emanuele Damiano, Mammi Isabella, Maretto Isacco, Enzo Maria Vittoria, Pastrello Chiara, Lise Mario, Nitti Donato, Viel Alessandra

Abstract excerpt

Biallelic germline mutations in the MYH gene cause MYH-Associated Polyposis but patients with a single mutation possibly have an increased colorectal cancer (CRC) risk. Using DNA from consecutive CRC patients we carried out a case-control study, with the aim to contribute data on the Italian population. Genotyping of four MYH mutations found two biallelic and two monoallelic carriers among 439 cases, and only one...

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Identifiers

PMID: 18495334
DOI: 10.1016/j.canlet.2008.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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