Article
Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.
International journal of cancer - 1 Nov 2011
Win Aung Ko, Cleary Sean P, Dowty James G, Baron John A, Young Joanne P, Buchanan Daniel D, Southey Melissa C, Burnett Terrilea, Parfrey Patrick S, Green Roger C, Le Marchand Loïc, Newcomb Polly A, Haile Robert W, Lindor Noralane M, Hopper John L, Gallinger Steven, Jenkins Mark A
Abstract excerpt
Cancer risks for a person who has inherited a MUTYH mutation from only one parent (monoallelic mutation carrier) are uncertain. Using the Colon Cancer Family Registry and Newfoundland Familial Colon Cancer Registry, we identified 2,179 first- and second-degree relatives of 144 incident colorectal...
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