Article
The distal region of 11p13 and associated genetic diseases.
Genomics - 1 Oct 1991
Mannens M, Hoovers J M, Bleeker-Wagemakers E M, Redeker E, Bliek J, Overbeeke-Melkert M, Saunders G, Williams B, van Heyningen V, Junien C
Abstract excerpt
The distal region of human chromosome band 11p13 is believed to contain a cluster of genes involved in the development of the eye, kidney, urogenital tract, and possibly the nervous system. Genetic abnormalities of this region can lead to Wilms tumor, aniridia, urogenital abnormalities, and menta...
Topics
- Adolescent
- Adult
- Alleles
- Aniridia
- Child
- Child, Preschool
- Chromosome Aberrations
- Chromosome Disorders
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- DNA Probes
- Disorders of Sex Development
- Female
- Genes, Tumor Suppressor
- Genes, Wilms Tumor
- Genetic Diseases, Inborn
- Humans
- Intellectual Disability