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Article

Stability of large segmental duplications in the yeast genome.

Genetics - 1 Apr 2006

Koszul Romain, Dujon Bernard, Fischer Gilles

Abstract excerpt

The high level of gene redundancy that characterizes eukaryotic genomes results in part from segmental duplications. Spontaneous duplications of large chromosomal segments have been experimentally demonstrated in yeast. However, the dynamics of inheritance of such structures and their eventual fixation in populations remain largely unsolved. We analyzed the stability of a vast panel of large segmental...

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Identifiers

PMID: 16489235
DOI: 10.1534/genetics.105.048058
PMCID: PMC1456401

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