Article
Gene conversion plays the major role in controlling the stability of large tandem repeats in yeast.
The EMBO journal - 1 Apr 1996
Gangloff S, Zou H, Rothstein R
Abstract excerpt
The genomic stability of the rDNA tandem array in yeast is tightly controlled to allow sequence homogenization and at the same time prevent deleterious rearrangements. In our study, we show that gene conversion, and not unequal sister chromatid exchange, is the predominant recombination mechanism regulating the expansion and contraction of the rDNA array. Furthermore, we found that RAD52, which is essential for...
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