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Article

The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression.

BMC medical genetics - 16 Feb 2006

Dempster Emma L, Mill Jonathan, Craig Ian W, Collier David A

Abstract excerpt

BACKGROUND: The COMT gene is located on chromosome 22q11, a region strongly implicated in the aetiology of several psychiatric disorders, in particular schizophrenia. Previous research has suggested that activity and expression of COMT is altered in schizophrenia, and is mediated by one or more polymorphisms within the gene, including the functional Val158Met polymorphism. METHOD: In this study we examined the...

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Identifiers

PMID: 16483362
DOI: 10.1186/1471-2350-7-10
PMCID: PMC1456954

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression.PMID 16483362Read ↗

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