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Article

Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development.

Genes & development - 15 Feb 2006

Suzuki Yo, Han Min

Abstract excerpt

Genetic redundancy is associated with a large percentage of genes. We investigated PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor gene functions that eluded single mutant analyses, using a Caenorhabditis elegans genome-wide screen. We show that at least 27 genes collaborate with the worm PTEN homolog daf-18 for various functions previously concealed by genetic redundancy,...

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Identifiers

PMID: 16481471
DOI: 10.1101/gad.1378906
PMCID: PMC1369044

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PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development.PMID 16481471Read ↗

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