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Article

A role for C. elegans Eph RTK signaling in PTEN regulation.

Developmental cell - 1 Oct 2009

Brisbin Sarah, Liu Jun, Boudreau Jeff, Peng Jimmy, Evangelista Marie, Chin-Sang Ian

Abstract excerpt

PTEN is one of the most commonly lost tumor suppressors in human cancer and is known to inhibit insulin signaling. Eph receptor tyrosine kinases (RTKs) have also been implicated in cancer formation and progression, and they have diverse functions, including nervous and vascular system development...

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Source

Identifiers

PMID: 19853560
DOI: 10.1016/j.devcel.2009.08.009

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19853560-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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A role for C. elegans Eph RTK signaling in PTEN regulation.PMID 19853560Read ↗

Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development.Semantic proximity Read ↗

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