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Article

Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): implications for schizophrenia.

Schizophrenia research - 1 Nov 2002

Tani Ayako, Kikuta Rumiko, Itoh Kanako, Joo Akiko, Shibata Hiroki, Ninomiya Hideaki, Tashiro Nobutada, Fukumaki Yasuyuki

Abstract excerpt

Dysfunction of the gene for the NR1 subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN1) has been implicated in the pathogenesis of schizophrenia. In support of this hypothesis are behavioral abnormalities reminiscent of schizophrenia in mice with an attenuated expression of the NR1 subunit receptor and the reduced level of NR1 mRNA in postmortem brains of patients with schizophrenia. We screened single...

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Source

Identifiers

PMID: 12363394
DOI: 10.1016/s0920-9964(02)00161-5

Genes

GRIN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): implications for schizophrenia.PMID 12363394Read ↗

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