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Article

Splice site requirement for the efficient accumulation of polyoma virus late mRNAs.

Nucleic acids research - 11 Jun 1991

Barrett N L, Carmichael G G, Luo Y

Abstract excerpt

Polyoma virus late nuclear primary transcripts are giant and heterogeneous, containing tandem repeats of the late strand of the circular viral genome. Late pre-mRNA processing involves the splicing of noncoding 'leader' exons to each other (removing genome-length introns), with the joining of the last leader to a coding 'body' exon. We have constructed a number of mutants blocked only in leader-leader splicing,...

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Identifiers

PMID: 1647524
DOI: 10.1093/nar/19.11.3011
PMCID: PMC328264

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