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Article

The sequence and context of the 5' splice site govern the nuclear stability of polyoma virus late RNAs.

Nucleic acids research - 11 Dec 1995

Barrett N L, Li X, Carmichael G G

Abstract excerpt

We have examined the influence of splicing signals on the stability of polyoma virus late RNAs in the nucleus. Late primary transcripts contain a single 5' splice site and three alternative 3' splice sites. In earlier work we showed that the presence of introns was not required for late RNA accumulation, however, the 5' splice site was essential, as removal of only the 5' splice site was sufficient to destabilize...

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Identifiers

PMID: 8532523
DOI: 10.1093/nar/23.23.4812
PMCID: PMC307469

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