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Article

X chromosomal abnormalities in basal-like human breast cancer.

Cancer cell - 1 Feb 2006

Richardson Andrea L, Wang Zhigang C, De Nicolo Arcangela, Lu Xin, Brown Myles, Miron Alexander, Liao Xiaodong, Iglehart J Dirk, Livingston David M, Ganesan Shridar

Abstract excerpt

Sporadic basal-like cancers (BLC) are a distinct class of human breast cancers that are phenotypically similar to BRCA1-associated cancers. Like BRCA1-deficient tumors, most BLC lack markers of a normal inactive X chromosome (Xi). Duplication of the active X chromosome and loss of Xi characterized almost half of BLC cases tested. Others contained biparental but nonheterochromatinized X chromosomes or gains of X...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16473279
DOI: 10.1016/j.ccr.2006.01.013

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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