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Article

BRCA1: An Unrecognized Modulator of Lineage Plasticity in Basal-like Breast Cancer.

Journal of mammary gland biology and neoplasia - 3 Dec 2025

Sanawar Rahul, Sengodan Satheesh Kumar

Abstract excerpt

Among breast cancer subtypes, basal-like breast cancer (BLBC) is a highly aggressive form characterized by a lack of estrogen receptor (ER), progesterone receptor (PR), and the human epidermal growth factor receptor (HER2) expression and is associated with poor prognosis, leaving chemotherapy as the sole treatment option available. Loss-of-function mutations in BRCA1 are strongly associated with the development...

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Identifiers

PMID: 41335251
DOI: 10.1007/s10911-025-09592-6
PMCID: PMC12779691

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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BRCA1: An Unrecognized Modulator of Lineage Plasticity in Basal-like Breast Cancer.PMID 41335251Read ↗

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