Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cAMP and cAMP-dependent protein kinase regulate the human heat shock protein 70 gene promoter activity.

The Journal of biological chemistry - 25 Jun 1991

Choi H S, Li B, Lin Z, Huang E, Liu A Y

Abstract excerpt

The theme of this study is an evaluation of the involvement of cAMP and cAMP-dependent protein kinase (PKA) in the regulation of the human heat shock protein (hsp) 70 gene promoter. Expression of a highly specific protein inhibitor of PKA (pRSVPKI) inhibited the basal as well as heat- and cadmium-induced expression of the cotransfected pHBCAT, a human hsp 70 promoter-driven reporter gene; this inhibition was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to DNA
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Vectors

Share to Mutation

Share to Promoter Regions, Genetic

Share to Protein Kinases

Share to Transfection

Source

Identifiers

PMID: 1646817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cAMP and cAMP-dependent protein kinase regulate the human heat shock protein 70 gene promoter activity.PMID 1646817Read ↗

TATA-dependent and TATA-independent function of the basal and heat shock elements of a human hsp70 promoter.Semantic proximity Read ↗

Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements.Semantic proximity Read ↗

A DNA motif related to the cAMP-responsive element and an exon-located activator protein-2 binding site in the human tissue-type plasminogen activator gene promoter cooperate in basal expression and convey activation by phorbol ester and cAMP.Semantic proximity Read ↗

An element within the 5′ untranslated region of human Hsp70 mRNA which acts as a general enhancer of mRNA translationSemantic proximity Read ↗

5-Aminolaevulinate synthase gene promoter contains two cAMP-response element (CRE)-like sites that confer positive and negative responsiveness to CRE-binding protein (CREB).Semantic proximity Read ↗

Role of protein kinase A in tax transactivation of the human T-cell leukemia virus type I long terminal repeat.Semantic proximity Read ↗

Adenovirus E1A represses the cyclic AMP-induced transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in hepatoma cells.Semantic proximity Read ↗

Transcriptional regulation of aquaporin-2 water channel gene by cAMP.Semantic proximity Read ↗

Ablation of stimulation of a cAMP-responsive promoter in CHO cell lines defective in their cAMP-dependent protein kinase system.Semantic proximity Read ↗

Transfection of a mutant regulatory subunit gene of cAMP-dependent protein kinase causes increased drug sensitivity and decreased expression of P-glycoprotein.Semantic proximity Read ↗

Response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids depends on the integrity of the cAMP pathway.Semantic proximity Read ↗

In vitro analysis of promoter elements regulating transcription of the phosphoenolpyruvate carboxykinase (GTP) gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.