Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of protein kinase A in tax transactivation of the human T-cell leukemia virus type I long terminal repeat.

Journal of virology - 1 May 1990

Kadison P, Poteat H T, Klein K M, Faller D V

Abstract excerpt

The human T-cell leukemia virus type I (HTLV-I) long terminal repeat (LTR) is inducible both by the retroviral tax gene product and by cyclic AMP in the murine thymoma S49 cell line. The cis-acting sequences that control transcriptional induction by tax and by cyclic AMP are in close proximity within the HTLV-I promoter. By using a protein kinase A (PKA)-deficient S49 mutant cell line, the response of the viral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2157876
DOI: 10.1128/JVI.64.5.2141-2148.1990
PMCID: PMC249372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of protein kinase A in tax transactivation of the human T-cell leukemia virus type I long terminal repeat.PMID 2157876Read ↗

Thyroid transcription factor 1 phosphorylation is not required for protein kinase A-dependent transcription of the thyroglobulin promoter.Semantic proximity Read ↗

Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes.Semantic proximity Read ↗

Protein kinase A activation of the surfactant protein B gene is mediated by phosphorylation of thyroid transcription factor 1.Semantic proximity Read ↗

Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C.Semantic proximity Read ↗

TAR independent activation of the human immunodeficiency virus in phorbol ester stimulated T lymphocytes.Semantic proximity Read ↗

Transfection of a mutant regulatory subunit gene of cAMP-dependent protein kinase causes increased drug sensitivity and decreased expression of P-glycoprotein.Semantic proximity Read ↗

A DNA motif related to the cAMP-responsive element and an exon-located activator protein-2 binding site in the human tissue-type plasminogen activator gene promoter cooperate in basal expression and convey activation by phorbol ester and cAMP.Semantic proximity Read ↗

Analysis of potential phosphorylation sites in human T cell leukemia virus type 1 Tax.Semantic proximity Read ↗

Combinatorial roles of protein kinase A, Ets2, and 3',5'-cyclic-adenosine monophosphate response element-binding protein-binding protein/p300 in the transcriptional control of interferon-tau expression in a trophoblast cell line.Semantic proximity Read ↗

The long terminal repeats of human immunodeficiency virus type-1 and human T-cell leukemia virus type-I are activated by 12-O-tetradecanoylphorbol-13-acetate through different pathways.Semantic proximity Read ↗

Regulation of protein kinase A activity by p90 ribosomal S6 kinase 1.Semantic proximity Read ↗

Ablation of stimulation of a cAMP-responsive promoter in CHO cell lines defective in their cAMP-dependent protein kinase system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.