Article
Role of protein kinase A in tax transactivation of the human T-cell leukemia virus type I long terminal repeat.
Journal of virology - 1 May 1990
Kadison P, Poteat H T, Klein K M, Faller D V
Abstract excerpt
The human T-cell leukemia virus type I (HTLV-I) long terminal repeat (LTR) is inducible both by the retroviral tax gene product and by cyclic AMP in the murine thymoma S49 cell line. The cis-acting sequences that control transcriptional induction by tax and by cyclic AMP are in close proximity wi...
Topics
- Adenylyl Cyclases
- Animals
- Base Sequence
- Blotting, Western
- Bucladesine
- Cell Line
- Chloramphenicol O-Acetyltransferase
- Chromosome Deletion
- Cyclic AMP
- Gene Expression
- Genes, Viral
- Human T-lymphotropic virus 1
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Plasmids
- Promoter Regions, Genetic
- Protein Kinases