Article
TATA-dependent and TATA-independent function of the basal and heat shock elements of a human hsp70 promoter.
Molecular and cellular biology - 1 Apr 1990
Greene J M, Kingston R E
Abstract excerpt
We have characterized the interactions between the TATA element and other sequence elements of a human heat shock protein 70 (hsp70) promoter by a mutational approach. Expression of a distal element of this promoter requires an intact TATA element in human cell lines. The hsp70 TATA element can b...
Topics
- Animals
- Base Sequence
- Cells, Cultured
- DNA-Directed RNA Polymerases
- HeLa Cells
- Heat-Shock Proteins
- Hot Temperature
- Humans
- Molecular Sequence Data
- Mutation
- Plasmids
- Promoter Regions, Genetic
- Transcription, Genetic
- Transfection
