Transcriptional regulation of aquaporin-2 water channel gene by cAMP.

doi:10.1681/ASN.V86861

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Article

Transcriptional regulation of aquaporin-2 water channel gene by cAMP.

Journal of the American Society of Nephrology : JASN - 1 Jun 1997

Matsumura Y, Uchida S, Rai T, Sasaki S, Marumo F

Abstract excerpt

Aquaporin-2 (AQP-2) water channel is a key molecule for urinary concentration whose expression is augmented by dehydration in vivo. To elucidate the regulatory mechanism of this phenomenon in vitro, mouse collecting duct cell lines were established from a transgenic mouse harboring temperature-se...

Topics

Animals
Aquaporin 2
Aquaporin 6
Aquaporins
Base Sequence
Cyclic AMP
Cyclic AMP Response Element-Binding Protein
Dehydration
Gene Expression Regulation
Genes
Humans
Ion Channels
Mice
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Rats
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 9189851
DOI: 10.1681/ASN.V86861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9189851-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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