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Article

Transcriptional regulation of aquaporin-2 water channel gene by cAMP.

Journal of the American Society of Nephrology : JASN - 1 Jun 1997

Matsumura Y, Uchida S, Rai T, Sasaki S, Marumo F

Abstract excerpt

Aquaporin-2 (AQP-2) water channel is a key molecule for urinary concentration whose expression is augmented by dehydration in vivo. To elucidate the regulatory mechanism of this phenomenon in vitro, mouse collecting duct cell lines were established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T antigen gene and then screened for the AQP-2 expression, using ribonuclease protection...

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PMID: 9189851
DOI: 10.1681/ASN.V86861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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