Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ZAP-70 expression in normal pro/pre B cells, mature B cells, and in B-cell acute lymphoblastic leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2006

Crespo Marta, Villamor Neus, Giné Eva, Muntañola Ana, Colomer Dolors, Marafioti Teresa, Jones Margaret, Camós Mireia, Campo Elias, Montserrat Emili, Bosch Francesc

Abstract excerpt

PURPOSE: The ZAP-70 gene is normally expressed in T and natural killer cells, where it is required for the T-cell receptor (TCR) signaling. More recently, it has been described that ZAP-70 contributes to the B-cell development at early stages of B-cell differentiation in mice. The purpose was to investigate the presence of ZAP-70 in normal pro/pre B cells and mature B cells and in tumoral cells from B-acute...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Burkitt Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Gene Expression Regulation, Leukemic

Share to Hematopoietic Stem Cells

Share to Phosphorylation

Share to Receptors, Antigen, T-Cell

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 16467082
DOI: 10.1158/1078-0432.CCR-05-1531

Genes

LAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ZAP-70 expression in normal pro/pre B cells, mature B cells, and in B-cell acute lymphoblastic leukemia.PMID 16467082Read ↗

ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype.Semantic proximity Read ↗

Clinical implications of ZAP-70 expressionin chronic lymphocytic leukemia.Semantic proximity Read ↗

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.Semantic proximity Read ↗

ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemiaSemantic proximity Read ↗

ZAP-70 in Signaling, Biology, and DiseaseSemantic proximity Read ↗

Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion.Semantic proximity Read ↗

Multicenter study of ZAP-70 expression in patients with B-cell chronic lymphocytic leukemia using an optimized flow cytometry method.Semantic proximity Read ↗

Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemiaSemantic proximity Read ↗

Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms.Semantic proximity Read ↗

ZAP-70 expression and prognosis in chronic lymphocytic leukaemia.Semantic proximity Read ↗

[Everything you ever wanted to know about ZAP-70].Semantic proximity Read ↗

Expression of ZAP-70 protein correlates with disease stage in chronic lymphocytic leukemia and is associated with, but not generally restricted to, non-mutated Ig VH status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.