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Article

ROS upregulation during the early phase of retroviral infection plays an important role in viral establishment in the host cell.

The Journal of general virology - 1 Oct 2013

Kim Soo Jin, Wong Paul K Y

Abstract excerpt

Recent studies suggest that low levels of reactive oxygen species (ROS) often modulate normal intracellular signalling pathways, determine cell fates and control cell proliferation. We found that infection of astrocytes with the neuropathogenic retrovirus ts1, a mutant of Moloney murine leukemia retrovirus, upregulated ROS at low levels during the early phase of infection. This upregulation of intracellular ROS...

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Identifiers

PMID: 23884362
DOI: 10.1099/vir.0.055228-0
PMCID: PMC3785033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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