Article
Tumor necrosis factor receptor‐1‐induced neuronal death by TRADD contributes to the pathogenesis of Japanese encephalitis
29 Jun 2007
Abstract excerpt
While a number of studies have documented the neurotropism of Japanese encephalitis virus (JEV), little is known regarding the molecular mechanism of neuronal death following viral infection. The tumor necrosis factor receptor (TNFR)-associated death domain (TRADD) has been suggested to be the crucial signal adaptor that mediates all intracellular responses from TNFR-1. Using mouse (Neuro2a) and human (SK-N-SH)...
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