Article
A better prognosis for genetic association studies in mice.
Trends in genetics : TIG - 1 Feb 2012
Zheng Ming, Dill David, Peltz Gary
Abstract excerpt
Although inbred mouse strains have been the premier model organism used in biomedical research, multiple studies and analyses have indicated that genome-wide association studies (GWAS) cannot be productively performed using inbred mouse strains. However, there is one type of GWAS in mice that has successfully identified the genetic basis for many biomedical traits of interest: haplotype-based computational...
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