Article
K-ras mutations in incident sporadic colorectal adenomas.
Cancer - 1 Mar 2006
Barry Elizabeth L R, Baron John A, Grau Maria V, Wallace Kristin, Haile Robert W
Abstract excerpt
BACKGROUND: Although K-ras is the most frequently mutated protooncogene in colorectal carcinoma, the specific role and timing of K-ras mutations in colorectal carcinogenesis remains controversial. In the current study, the authors investigated associations with K-ras mutation in incident sporadic...
Topics
- Adenoma
- Adult
- Aged
- Cell Transformation, Neoplastic
- Chromatography, High Pressure Liquid
- Colorectal Neoplasms
- DNA Mutational Analysis
- Female
- Genes, ras
- Genotype
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction