Article
Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas.
Cancer research - 15 Oct 1999
Martínez M E, Maltzman T, Marshall J R, Einspahr J, Reid M E, Sampliner R, Ahnen D J, Hamilton S R, Alberts D S
Abstract excerpt
The Ki-ras protooncogene frequently is mutated in colorectal adenocarcinomas, but the etiology of this molecular event is uncertain. We investigated the association between variables known or suspected to be related to risk for colorectal cancer and the occurrence of Ki-ras mutations in colorectal adenomas. This study was conducted among 678 male and female participants, 40-80 years of age, enrolled in a phase...
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