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Article

Differential role for cyclic AMP response element binding protein-1 in multiple stages of B cell development, differentiation, and survival.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2006

Chen Hui-Chen, Byrd John C, Muthusamy Natarajan

Abstract excerpt

CREB-1 is expressed in the bone marrow and in developing B cells. To determine the role of CREB-1 in developing B cells in the bone marrow, several lines of transgenic (Tg) mice overexpressing a dominant-negative Ser(119-ala) phosphomutant CREB-1 in the bone marrow were generated. Analysis of RNA and protein revealed expression of the transgene in the bone marrow. Flow cytometric analysis of bone marrow cells...

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Identifiers

PMID: 16455977
DOI: 10.4049/jimmunol.176.4.2208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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