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Article

The effects of c-Abl mutation on developing B cell differentiation and survival.

International immunology - 1 May 2009

Brightbill Hans, Schlissel Mark S

Abstract excerpt

c-Abl is a widely expressed Src family protein tyrosine kinase that is activated by chromosomal translocation in certain human leukemias. While shown in various experimental systems to regulate cell division and stress responses, its biological functions remain poorly understood. Although expressed at similar levels throughout B cell development, we found that the fraction of phosphorylated, active c-Abl peaks at...

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Identifiers

PMID: 19299624
DOI: 10.1093/intimm/dxp027
PMCID: PMC2675032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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