Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of the heme oxygenase-1 gene and cerebral aneurysms.

British journal of neurosurgery - 1 Aug 2005

Morgan L, Hawe E, Palmen J, Montgomery H, Humphries S E, Kitchen N

Abstract excerpt

Inflammation is thought to play an important role in intracranial aneurysm formation. Heme-oxygenase-1(HO-1) is a novel anti-inflammatory factor. A length polymorphic variant of the HO-1 gene promoter region, comprising (GT)n dinucleotide repeats, is associated with altered levels of gene transcription: long (= 36 GT) repeats are associated with decreased HO-1. We hypothesized that patients with aneurysmal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heme Oxygenase-1

Share to Intracranial Aneurysm

Share to Microsatellite Repeats

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16455537
DOI: 10.1080/02688690500305456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of the heme oxygenase-1 gene and cerebral aneurysms.PMID 16455537Read ↗

Heme oxygenase-1 gene promoter polymorphism is associated with abdominal aortic aneurysm.Semantic proximity Read ↗

The effect of a promoter polymorphism in the heme oxygenase-1 gene on the risk of ischaemic cerebrovascular events: the influence of other vascular risk factors.Semantic proximity Read ↗

The interleukin-6 gene -174G>C and -572G>C promoter polymorphisms are related to cerebral aneurysms.Semantic proximity Read ↗

Vascular endothelial growth factor gene polymorphisms and intracranial aneurysms.Semantic proximity Read ↗

GT microsatellite repeats in the heme oxygenase-1 gene promoter associated with abdominal aortic aneurysm in Croatian patients.Semantic proximity Read ↗

Gene Polymorphisms Increasing the Risk of Intracranial Aneurysms: Interleukin-6 -174G>C and -572G>C (Part II).Semantic proximity Read ↗

Tumor necrosis factor-alpha gene and cerebral aneurysms.Semantic proximity Read ↗

Relationship between endothelial nitric oxide synthase (eNOS) and natural history of intracranial aneurysms: meta-analysis.Semantic proximity Read ↗

Association of HO-1 (GT)n Promoter Polymorphism and Cardiovascular Disease: A Reanalysis of the Literature.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage and cerebral vasospasm.Semantic proximity Read ↗

Gene Polymorphisms Increasing the Risk of Intracranial Aneurysms: Interleukin-1β -511C>T (Part I).Semantic proximity Read ↗

Haptoglobin Genotype Affects Inflammation after Aneurysmal Subarachnoid Hemorrhage.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.