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Article

In vivo analysis of a gain-of-function mutation in the Drosophila eag-encoded K+ channel.

Genetics - 1 Apr 2006

Cardnell Robert J G, Nogare Damian E Dalle, Ganetzky Barry, Stern Michael

Abstract excerpt

Neuronal Na+ and K+ channels elicit currents in opposing directions and thus have opposing effects on neuronal excitability. Mutations in genes encoding Na+ or K+ channels often interact genetically, leading to either phenotypic suppression or enhancement for genes with opposing or similar effects on excitability, respectively. For example, the effects of mutations in Shaker (Sh), which encodes a K+ channel...

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Identifiers

PMID: 16452147
DOI: 10.1534/genetics.105.048777
PMCID: PMC1456403

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Source receipt: pubmed, retrieved 7 Sept 2026.

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