Article
Alteration of four identified K+ currents in Drosophila muscle by mutations in eag.
Science (New York, N.Y.) - 14 Jun 1991
Zhong Y, Wu C F
Abstract excerpt
Voltage-clamp analysis of Drosophila larval muscle revealed that ether à go-go (eag) mutations affected all identified potassium currents, including those specifically eliminated by mutations in the Shaker or slowpoke gene. Together with DNA sequence analysis, the results suggest that the eag locus encodes a subunit common to different potassium channels. Thus, combinatorial assembly of polypeptides from...
Topics
- 4-Aminopyridine
- Animals
- Calcium
- Chromosome Mapping
- Drosophila
- Electric Stimulation
- Kinetics
- Larva
- Membrane Potentials
- Muscles
- Mutation
- Potassium Channels