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Article

Seizure suppression by shakB2, a gap junction mutation in Drosophila.

Journal of neurophysiology - 1 Feb 2006

Song Juan, Tanouye Mark A

Abstract excerpt

Gap junction proteins mediate electrical synaptic transmission. In Drosophila, flies carrying null mutations in the shakB locus, such as shakB2, have behavioral and electrophysiological defects in the giant fiber (GF) system neurocircuit consistent with a loss of transmission at electrical synapses. The shakB2 mutation also affects seizure susceptibility. Mutant flies are especially seizure-resistant and have a...

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Identifiers

PMID: 16192342
DOI: 10.1152/jn.01059.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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