Article
The seizure locus encodes the Drosophila homolog of the HERG potassium channel.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Feb 1997
Wang X J, Reynolds E R, Déak P, Hall L M
Abstract excerpt
Mutations in the seizure (sei) locus cause temperature-induced hyperactivity, followed by paralysis. Gene cloning studies have established that the seizure gene product is the Drosophila homolog of HERG, a member of the eag family of K+ channels implicated in one form of hereditary long QT syndro...
Topics
- Amino Acid Sequence
- Animals
- Cation Transport Proteins
- Chromosome Mapping
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- ERG1 Potassium Channel
- Ether-A-Go-Go Potassium Channels
- Gene Expression Regulation
- Humans
- Hyperkinesis
- Long QT Syndrome
- Molecular Sequence Data
- Mutation
- Paralysis
- Potassium Channels
- Potassium Channels, Voltage-Gated