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Article

Comparative informativeness for linkage of multiple SNPs and single microsatellites.

Human heredity - 1 Jan 2004

Lindholm Eva, Hodge Susan E, Greenberg David A

Abstract excerpt

Single nucleotide polymorphisms (SNPs), or biallelic markers, are popular in genetic linkage studies due to their abundance in the genome, stability, and ease of scoring. We determined the 'information ratio' (IR) of closely spaced SNPs in simulated nuclear families and affected sib pairs (ASPs). (The IR is the ratio of actual average maximum lod score to the maximum lod score attainable if the marker were fully...

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PMID: 15812173
DOI: 10.1159/000083543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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