Article
DLG5 variants contribute to Crohn disease risk in a Canadian population.
Human mutation - 1 Apr 2006
Newman William G, Gu Xiangjun, Wintle Richard F, Liu Xiangdong, van Oene Mark, Amos Christopher I, Siminovitch Katherine A
Abstract excerpt
Variants in the gene encoding the DLG5 scaffolding protein have been reported to be associated with increased risk of inflammatory bowel disease (IBD) and particularly Crohn's disease (Crohn disease; CD). These findings have not been uniformly replicated in follow-up studies. In this study we genotyped a cohort of 402 Canadian CD and 179 ulcerative colitis (UC) patients and 537 healthy controls for three...
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