Article
Role of the IBD5 susceptibility locus in the inflammatory bowel diseases.
Inflammatory bowel diseases - 1 Mar 2006
Reinhard Claudia, Rioux John D
Abstract excerpt
The field of inflammatory bowel disease genetics plays a leading role in the genetics of complex traits. One of the first genetic loci for a complex trait to be identified by genome-wide linkage scans and confirmed by multiple studies was IBD1 for Crohn's disease. Shortly after this initial success, a second susceptibility locus, the IBD5 risk haplotype, was discovered and unequivocally replicated. In this...
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