Article
Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population.
International journal of colorectal disease - 1 Apr 2007
Pearce Alexandra V, Fisher Sheila A, Prescott Natalie J, Onnie Clive M, Pattni Reenal, Green Peter, Forbes Alastair, Mansfield John, Sanderson Jeremy, Schreiber Stefan, Lewis Cathryn M, Mathew Christopher G
Abstract excerpt
BACKGROUND AND AIMS: Mutations in the DLG5 gene are associated with an increased risk of inflammatory bowel disease (IBD) in some European populations. Initial investigation of a British IBD population showed evidence of association of one of three DLG5 variants, R30Q, in a family-based collection but not in a case-control cohort. We have now examined the association of the R30Q polymorphism in a large cohort of...
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