Article
Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
Journal of human genetics - 1 Jan 2004
Yamazaki Keiko, Takazoe Masakazu, Tanaka Torao, Ichimori Toshiki, Saito Susumu, Iida Aritoshi, Onouchi Yoshihiro, Hata Akira, Nakamura Yusuke
Abstract excerpt
Crohn disease (CD) is an inflammatory bowel disease characterized by chronic transmural, segmental, and typically granulomatous inflammation of the gut. Recently, two novel candidate gene loci associated with CD, SLC22A4 and SLC22A5 on chromosome 5 known as IBD5 and DLG5 on chromosome 10, were identified through association analysis of Caucasian CD patients. We validated these candidate genes in Japanese patients...
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