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Article

Establishment of three human breast epithelial cell lines derived from carriers of the 999del5 BRCA2 Icelandic founder mutation.

In vitro cellular & developmental biology. Animal - 1 Jan 2000

Rubner Fridriksdottir Agla J, Gudjonsson Thorarinn, Halldorsson Thorhallur, Björnsson Johannes, Steinarsdottir Margret, Johannsson Oskar Thor, Ogmundsdottir Helga M

Abstract excerpt

Germ line mutations in BRCA1 and BRCA2 account for a large proportion of inherited breast and ovarian cancer. Both genes are involved in DNA repair by homologous recombination and are thought to play a vital role in maintaining genomic stability. A major drawback for long-term functional studies...

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Source

Identifiers

PMID: 16448223
DOI: 10.1007/s11626-005-0005-3

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16448223-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Establishment of three human breast epithelial cell lines derived from carriers of the 999del5 BRCA2 Icelandic founder mutation.PMID 16448223Read ↗

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