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Article

De novo recurrent germline mutation of the BRCA2 gene in a patient with early onset breast cancer.

Journal of medical genetics - 1 Feb 2001

van der Luijt R B, van Zon P H, Jansen R P, van der Sijs-Bos C J, Wárlám-Rodenhuis C C, Ausems M G

Abstract excerpt

Germline mutations in either of the two major breast cancer predisposition genes, BRCA1 and BRCA2, account for a significant proportion of hereditary breast/ovarian cancer. Identification of breast cancer patients carrying mutations of these genes is primarily based on a positive family history of breast/ovarian cancer or early onset of the disease or both. In the course of mutation screening of the BRCA1 and...

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Source

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Identifiers

PMID: 11158174
DOI: 10.1136/jmg.38.2.102
PMCID: PMC1734809

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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