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Article

The testis-specific apoptosis related gene TTL.6 underwent adaptive evolution in the lineage leading to humans.

Gene - 29 Mar 2006

Chen Xiao-hua, Shi Hong, Liu Xiao-Lin, Su Bing

Abstract excerpt

The TTL.6 gene is a member of the tubulin-tyrosine ligase (TTL) family involved in apoptosis and preferentially expressed in the testis. We sequenced the coding region and part of the introns of TTL.6 in world wide human populations and five representative nonhuman primate species covering great apes, lesser ape and Old World monkey. The sequence substitution patterns of TTL.6 in primates demonstrated a sharp...

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Source

Identifiers

PMID: 16443334
DOI: 10.1016/j.gene.2005.11.014

Genes

TTL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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