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Article

Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs.

Molecular biology and evolution - 1 Oct 2005

Osada Naoki, Hirata Makoto, Tanuma Reiko, Kusuda Jun, Hida Munetomo, Suzuki Yutaka, Sugano Sumio, Gojobori Takashi, Shen C-K James, Wu Chung-I, Hashimoto Katsuyuki

Abstract excerpt

The substitution rate and structural divergence in the 5'-untranslated region (UTR) were investigated by using human and cynomolgus monkey cDNA sequences. Due to the weaker functional constraint in the UTR than in the coding sequence, the divergence between humans and macaques would provide a good estimate of the nucleotide substitution rate and structural divergence in the 5'UTR. We found that the substitution...

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PMID: 15944441
DOI: 10.1093/molbev/msi187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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