Article

Rapid evolution of the embryonically-expressed homeobox gene <i>LEUTX</i> within primates

2023-02-02

Abstract excerpt

LEUTX is a homeodomain transcription factor expressed in the very early embryo with a function around embryonic genome activation. The LEUTX gene is found only in eutherian mammals, including humans, but unlike the majority of homeobox genes, the encoded amino acid sequence is very different between divergent mammalian species. However, whether dynamic evolution has also occurred between closely related mammalian...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d45d9f2c-dfd7-5a38-a59a-fef033f9dd94
DOI: 10.1101/2023.02.02.526829

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rapid evolution of the embryonically-expressed homeobox gene <i>LEUTX</i> within primatesDOI 10.1101/2023.02.02.526829Read

The human PRD-like homeobox gene <i>LEUTX</i> has a central role in embryo genome activationSemantic proximity Read

The origin and evolution of ARGFX homeobox loci in mammalian radiation.Semantic proximity Read

A single mutation in ACTR8 gene results in lineage-specific expression in primatesSemantic proximity Read

Cooption of polyalanine tract into a repressor domain in the mammalian transcription factor HoxA11Semantic proximity Read

The testis-specific apoptosis related gene TTL.6 underwent adaptive evolution in the lineage leading to humans.Semantic proximity Read

Molecular evolution of the homeodomain family of transcription factors.Semantic proximity Read

An homeotic post-transcriptional network controlled by the RNA-binding protein RBMXSemantic proximity Read

LEUTX regulates porcine embryonic genome activation in somatic cell nuclear transfer embryosSemantic proximity Read

Widespread <i>cis</i> -regulation of RNA-editing in a large mammalSemantic proximity Read

Gene expansion and retention leads to a diverse tyrosine kinase superfamily in amphioxus.Semantic proximity Read

Bidirectional promoters as important drivers for the emergence of species-specific transcripts.Semantic proximity Read

The 3D-Evo Space: Evolution of Gene Expression and Alternative Splicing Regulation.Semantic proximity Read