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Article

A single mutation in the ACTR8 gene associated with lineage-specific expression in primates.

BMC evolutionary biology - 5 Jun 2020

Choe Se-Hee, Park Sang-Je, Cho Hyeon-Mu, Park Hye-Ri, Lee Ja-Rang, Kim Young-Hyun, Huh Jae-Won

Abstract excerpt

BACKGROUND: Alternative splicing (AS) generates various transcripts from a single gene and thus plays a significant role in transcriptomic diversity and proteomic complexity. Alu elements are primate-specific transposable elements (TEs) and can provide a donor or acceptor site for AS. In a study on TE-mediated AS, we recently identified a novel AluSz6-exonized ACTR8 transcript of the crab-eating monkey (Macaca...

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Identifiers

PMID: 32503430
DOI: 10.1186/s12862-020-01620-9
PMCID: PMC7275561

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