Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ubiquilin gene family: evolutionary patterns and functional insights

1 Jan 2014

Abstract excerpt

BACKGROUND: Ubiquilins are proteins that function as ubiquitin receptors in eukaryotes. Mutations in two ubiquilin-encoding genes have been linked to the genesis of neurodegenerative diseases. However, ubiquilin functions are still poorly understood. RESULTS: In this study, evolutionary and functional data are combined to determine the origin and diversification of the ubiquilin gene family and to characterize...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer-related Molecular Pathways
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24674348
DOI: 10.1186/1471-2148-14-63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ubiquilin gene family: evolutionary patterns and functional insightsPMID 24674348Read ↗

Ubiquilin 2: A component of the ubiquitin–proteasome system with an emerging role in neurodegenerationSemantic proximity Read ↗

A new Drosophila model of Ubiquilin knockdown shows the effect of impaired proteostasis on locomotive and learning abilities.Semantic proximity Read ↗

Evolution of the F-box gene family in Euarchontoglires: gene number variation and selection patterns.Semantic proximity Read ↗

Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinerySemantic proximity Read ↗

Reconstructing the phylogeny of 21 completely sequenced arthropod species based on their motor proteinsSemantic proximity Read ↗

Animal HECT ubiquitin ligases: evolution and functional implicationsSemantic proximity Read ↗

Profilin Isoforms in Health and Disease – All the Same but DifferentSemantic proximity Read ↗

The diversification of the LIM superclass at the base of the metazoa increased subcellular complexity and promoted multicellular specialization.Semantic proximity Read ↗

Comparative Genomics of the RBR Family, Including the Parkinson's Disease–Related Gene Parkin and the Genes of the Ariadne SubfamilySemantic proximity Read ↗

Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade MetazoaSemantic proximity Read ↗

MOXD2, a Gene Possibly Associated with Olfaction, Is Frequently Inactivated in Birds.Semantic proximity Read ↗

Insights into the Molecular Evolution of the PDZ/LIM Family and Identification of a Novel Conserved Protein MotifSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.