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Article

Molecular cloning and characterization of a novel human ribonuclease (RNase k6): increasing diversity in the enlarging ribonuclease gene family.

Nucleic acids research - 15 Sept 1996

Rosenberg H F, Dyer K D

Abstract excerpt

The discovery of Ribonuclease k6 (RNase k6) was an unexpected result of our ongoing efforts to trace the evolutionary history of the ribonuclease gene family. The open reading frame of RNase k6, amplified from human genomic DNA, encodes a 150 amino acid polypeptide with eight cysteines and histidine and lysine residues corresponding to those found in the active site of the prototype, ribonuclease A. The...

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Identifiers

PMID: 8836175
DOI: 10.1093/nar/24.18.3507
PMCID: PMC146131

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