Article
The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis.
Genes & development - 1 Aug 1992
Rutledge B J, Zhang K, Bier E, Jan Y N, Perrimon N
Abstract excerpt
We describe the molecular characterization of the Drosophila gene spitz (spi), which encodes a putative 26-kD, EGF-like transmembrane protein that is structurally similar to TGF-alpha. Temporal and spatial expression patterns of spi transcripts indicate that spi is expressed throughout the embryo...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Epidermal Growth Factor
- Larva
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Recombinant Fusion Proteins