Article
EGFR signaling is required for the differentiation and maintenance of neural progenitors along the dorsal midline of the Drosophila embryonic head.
Development (Cambridge, England) - 1 Sept 1998
Dumstrei K, Nassif C, Abboud G, Aryai A, Aryai A, Hartenstein V
Abstract excerpt
EGFR signaling has been shown in recent years to be involved in the determination, differentiation and maintenance of neural and epidermal cells of the ventral midline (mesectoderm and ventromedial ectoderm). Localized activation of the TGFalpha homolog Spitz (Spi) in the mesectoderm is achieved...
Topics
- Animals
- Body Patterning
- Cell Differentiation
- Drosophila
- Ectoderm
- Epithelial Cells
- ErbB Receptors
- Gene Expression Regulation, Developmental
- Genes, Insect
- Head
- Mutation
- Nervous System
- Neurons
- Signal Transduction
- Stem Cells