The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family.

doi:10.1016/0092-8674(95)90539-1

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Article

The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family.

Cell - 2 Jun 1995

Arora K, Dai H, Kazuko S G, Jamal J, O'Connor M B, Letsou A, Warrior R

Abstract excerpt

Decapentaplegic (dpp), a TGF beta-related ligand, plays a key role in Drosophila development. Although dpp receptors have been isolated, the downstream components of the signaling pathway remain to be identified. We have cloned the schnurri (shn) gene and show that it encodes a putative zinc finger transcription factor homologous to the human major histocompatibility complex-binding proteins 1 and 2. Mutations in...

Topics

Amino Acid Sequence
Animals
Base Sequence
Bone Morphogenetic Proteins
Cloning, Molecular
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Ectoderm
Genes, Insect
Histocytochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insect Hormones

Mesoderm

Molecular Sequence Data

Mutation

Proteins

RNA, Messenger

Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 7774017
DOI: 10.1016/0092-8674(95)90539-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7774017-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family.PMID 7774017Read ↗

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