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Article

The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-beta superfamily.

Science (New York, N.Y.) - 25 Mar 1994

Xie T, Finelli A L, Padgett R W

Abstract excerpt

The Drosophila decapentaplegic (dpp) gene encodes a transforming growth factor-beta (TGF-beta)-like protein that plays a key role in several aspects of development. Transduction of the DPP signal was investigated by cloning of serine-threonine kinase transmembrane receptors from Drosophila because this type of receptor is specific for the TGF-beta-like ligands. Here evidence is provided demonstrating that the...

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PMID: 8134837
DOI: 10.1126/science.8134837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-beta superfamily.PMID 8134837Read ↗

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An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.Semantic proximity Read ↗

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